iThera Multispcetoral Optoacoustic Tomography
Description
Optoacoustic or photoacoustic imaging is a new, cutting-edge imaging technique which detects ultrasound waves following light absorption from specific molecules. This technique allows molecules with different spectral profile to be detected. For example, the different spectral properties of oxygenated haemoglobin and deoxygenated haemoglobin can be used for monitoring changes in soluble oxygen of tissue and organs, allowing quantification of vascular changes without a contrast agent. Advancements in the development of nanoparticles and infrared fluorescent reporters that are detectable by optoacoustics have also increased the possibilities of molecular imaging. Gold nanoparticle is one of the contrast agents that can be visualised with optoacoustics and microCT scan.
Specifications
The Multispectral Optoacoustic Tomography (MSOT) inVision256-TF (iThera Medical) was acquired with the help of the Cancer Institute NSW equipment grant 2014. It is the only system capable of multispectral tomographic imaging of an entire mouse and will expand our ability for multimodal imaging.
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- Laser wavelength 680-980 nmÂ
- Â 256 detector elementsÂ
- Real-time image acquisition at an imaging rate of 10 frames per secondÂ
- Spatial resolution 150 nmÂ
- Lower limit quantification: ICG- 50nM, Gold Nanoparticles- 15fM
- Integrated CryoMOUSEâ„¢ reference anatomy
Applications
- Blood oxygenationÂ
- Tracer imaging
.cropimg.width=335.crop=square.jpg "Vega Preclinical Ultrasound (stock) MWAC-BRIL")
Instrument location
Biological Resources Imaging Laboratory
Basement
Lowy Cancer Research Centre (C25)
̽»¨ÏµÁÐ Sydney, NSW 2033
Phone:Â 02Â 9065 9836
·¡³¾²¹¾±±ô:Ìýbril@unsw.edu.au
Tzong Tyng Hung
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Phone
02 9065 8902 -
Email
t.hung@unsw.edu.au
Brendan Lee
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Phone
02 9065 9836 -
Email
b.j.lee@unsw.edu.au
Parent facility
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